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Pyridostigmine is a parasympathomimetic and a reversible cholinesterase inhibitor. Since it is a quaternary amine, it is poorly absorbed in the gut and does not cross
Immediate medical attention is necessary for a methadone overdose, as it can be fatal. This eMedTV page lists possible overdose symptoms (such as breathing problems

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Management of Psychotherapeutic Drug Overdoses
Management of Psychotherapeutic Drug Overdoses Lisa Booze, PharmD, CSPI lbooze@rx.umaryland.edu
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